Table 3. Biometric, biochemical and cardiovascular parameters of rats fed a control diet (CT) or a high-fat diet (FAT), and submitted to physical training (PT) or kept sedentary (SED).
CT diet | FAT diet | |||
---|---|---|---|---|
SED | PT | SED | PT | |
Total cholesterol (mmol/l) | 1.8 ± 0.03 | 1.7 ± 0.08 | 2.1 ± 0.03* | 1.8 ± 0.07 |
ALT (U/l) | 54.2 ± 1.2 | 62.4 ± 3.1 | 68.2 ± 3.4* | 70.0 ± 3.5* |
AST (U/l) | 8.1 ± 2.2 | 14.9 ± 4.3 | 5.3 ± 1.8 | 11.1 ± 3.1 |
Albumin (µmol/l) | 4.1 ± 0.1 | 4.1 ± 0.06 | 4.1 ± 0.08 | 4.06 ± 0.09 |
Glycemia (mmol/l) | 6.2 ± 0.2 | 6.5 ± 0.3 | 7.2 ± 0.1* | 6.6 ± 0.2 |
Insulin (ng/ml) | 1.3 ± 0.2 | 1.5 ± 0.3 | 2.4 ± 0.1* | 1.4 ± 0.2 |
Lactate (mmol/l) | 9.41 ± 1.2 | 10.2 ± 2.4 | 16.9 ± 0.9* | 8.03 ± 0.2# |
MAP (mmHg) | 109 ± 5.8 | 125 ± 5.2 | 147 ± 5.7* | 107 ± 11.7# |
HR (beats/min) | 369 ± 7.8 | 338 ± 27.5 | 435 ± 7.2* | 384 ± 4.6# |
Liver (g/100 g body mass) | 3.3 ± 0.08 | 3.2 ± 0.04 | 3.0 ± 0.05 | 3.0 ± 0.04 |
Retroperitoneal fat (g/100 g body mass) | 1.66 ± 0.1 | 1.49 ± 0.1 | 3.42 ± 0.1* | 2.5 ± 0.09# |
Body mass (g) | 287 ± 3.6 | 263 ± 6.1 | 336 ± 9.6* | 289.6 ± 9# |
N | 5–6 | 5–6 | 5–6 | 5–6 |
Fischer rats fed a high-fat diet (30% fat, FAT) or a control diet (AIN-93, CT) for 13 weeks and submitted to physical training (PT) or maintained sedentary (SED) during the last 6 weeks of diet. ALT, alanine aminotransferase; AST, aspartate aminotransferase.
*P < 0.05 compared to CT-SED group.
#P < 0.05 compared to FAT- SED group (two-way ANOVA followed by Bonferroni post-test).