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. 2017 May 5;22(6):556–562. doi: 10.1080/13510002.2017.1322750

Table 5. Activities of phase 1 enzymes [aniline hydroxylase (AnH) and aminopyrine-N-demethylase (AmD)] and phase II enzyme (UDPGT) in the testis of rats treated with NDMA and BA (alone and in combination).

Treatments groups AnH AmD UDPGT
(μmol/mg protein) (mmol/mg protein)
Control 0.398 ± 0.59 0.530 ± 0.01 0.12 ± 0.02
BA 1.014 ± 098a 0.485 ± 0.01a 0.14 ± 0.03a
NDMA 1.694 ± 0.86b 0.840 ± 0.08b 0.07 ± 0.007b
BA + NDMA 0.910 ± 0.21c 0.612 ± 0.03c 0.10 ± 0.03c

Data expressed as mean ± S.D. (n = 6).

aStatistically similar to [BA + NDMA] (P > 0.001).

bStatistically different from control (P < 0.05).

cStatistically different from NDMA (P < 0.05).

BA: betulinic acid; NDMA: N-nitrosodimethylamine.