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. 2022 Mar 7;10:tkac009. doi: 10.1093/burnst/tkac009

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© The Author(s) 2022. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 8. — Upregulation of circRNA_Maml2 promotes the repair of damaged intestinal mucosa after severe burns. (a) Expression of circRNA_Maml2 was detected by qRT-PCR in the control group, burn group and burn+Ad-circRNA_Maml2 group. (b) Expression of miR-93-3p was detected by qRT-PCR in the control group, burn group and burn+Ad-circRNA_Maml2 group. (c, d) Expression of Fzd7 mRNA and FZD7 protein was detected by qRT-PCR in the control group, burn group and burn+Ad-circRNA_Maml2 group. (e) Injury of the intestinal mucosa under light microscope in the control group, burn group and burn+Ad-circRNA_Maml2 group. (f) HE staining revealed the damage of the intestinal mucosa in the control group, burn group and burn+Ad-circRNA_Maml2 group. (g) Expression level of DAO revealed the damage to the intestinal mucosa in the control group, burn group and burn+Ad-circRNA_Maml2 group. *p < 0.05, **p < 0.01, ***p < 0.001. Ad Adenovirus, Fzd7 frizzled class receptor 7, qRT-PCR quantitative real-time polymerase chain reaction, U6 U6 small nuclear RNA, HE hematoxylin and eosin, DAO diamine oxidase