Table 2. Metabolic profile in NPDR.
Placebo (n = 20) |
Coenzyme Q10 (n = 20) |
Combined antioxidant therapy (n = 20) |
||||||||
---|---|---|---|---|---|---|---|---|---|---|
Baseline | Final | P | Baseline | Final | P | Baseline | Final | P | P | |
WCX | WCX | WCX | K–W | |||||||
Glycated hemoglobin (HbA1c, %) | 9.22 ± 0.39 | 8.01 ± 0.4 | 0.048 | 8.5 ± 0.4 | 8.3 ± 0.4 | NS | 9.6 ± 0.4 | 8.6 ± 0.2 | 0.05 | NS |
Glucose (mg/dl) | 125.2 ± 8.0 | 135.3 ± 12.4 | NS | 149.1 ± 12.9 | 135.7 ± 11.0 | NS | 149.4 ± 13.5 | 124.7 ± 10.2 | NS | NS |
Total cholesterol (TC, mg/dl) | 200.6 ± 7.1 | 195.5 ± 7.1 | NS | 176.8 ± 7.4 | 169.2 ± 9.8 | NS | 205.0 ± 8.1 | 200.4 ± 8.6 | NS | NS |
Low-density cholesterol (LDL, mg/dl) | 129.5 ± 15.6 | 115.9 ± 7.8 | NS | 90.3 ± 5.2 | 94.3 ± 5.7 | NS | 114.8 ± 7.1 | 110.6 ± 6.9 | NS | NS |
High-density cholesterol (HDL, mg/dl) | 47.3 ± 3.5 | 46.5 ± 2.3 | NS | 42.9 ± 2.1 | 46.1 ± 2.6 | NS | 41.8 ± 1.1 | 46.9 ± 2.6 | NS | NS |
Triglycerides (TGC, mg/dl) | 214.3 ± 22.4 | 180.4 ± 17.6 | NS | 210.0 ± 28.5 | 198.5 ± 20.4 | NS | 252.8 ± 27.3 | 223.4 ± 25.7 | NS | NS |
The table illustrates metabolic profile per study group, where values are expressed as mean ± standard error. There was a significant decrease in HbA1c in the Placebo (P < 0.048) and combined antioxidant therapy groups (P < 0.05). These improvements could be due to close medical attention or lifestyle changes.
NPDR, non-proliferative diabetic retinopathy; HBA1c, glycated hemoglobin, %, percent, TC, total cholesterol; LDC, low-density cholesterol; HDL, high-density cholesterol; TGC, triglycerides; mg/dl, milligram/deciliter, NS, not significant; WCX, Wilcoxon test, K–W, Kruskal–Wallis test.