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. 2015 Aug 31;21(4):155–163. doi: 10.1179/1351000215Y.0000000040

Table 2. Metabolic profile in NPDR.

  Placebo (n = 20)
Coenzyme Q10 (n = 20)
Combined antioxidant therapy (n = 20)
  Baseline Final P Baseline Final P Baseline Final P P
      WCX     WCX     WCX K–W
Glycated hemoglobin (HbA1c, %) 9.22 ± 0.39 8.01 ± 0.4 0.048 8.5 ± 0.4 8.3 ± 0.4 NS 9.6 ± 0.4 8.6 ± 0.2 0.05 NS
Glucose (mg/dl) 125.2 ± 8.0 135.3 ± 12.4 NS 149.1 ± 12.9 135.7 ± 11.0 NS 149.4 ± 13.5 124.7 ± 10.2 NS NS
Total cholesterol (TC, mg/dl) 200.6 ± 7.1 195.5 ± 7.1 NS 176.8 ± 7.4 169.2 ± 9.8 NS 205.0 ± 8.1 200.4 ± 8.6 NS NS
Low-density cholesterol (LDL, mg/dl) 129.5 ± 15.6 115.9 ± 7.8 NS 90.3 ± 5.2 94.3 ± 5.7 NS 114.8 ± 7.1 110.6 ± 6.9 NS NS
High-density cholesterol (HDL, mg/dl) 47.3 ± 3.5 46.5 ± 2.3 NS 42.9 ± 2.1 46.1 ± 2.6 NS 41.8 ± 1.1 46.9 ± 2.6 NS NS
Triglycerides (TGC, mg/dl) 214.3 ± 22.4 180.4 ± 17.6 NS 210.0 ± 28.5 198.5 ± 20.4 NS 252.8 ± 27.3 223.4 ± 25.7 NS NS

The table illustrates metabolic profile per study group, where values are expressed as mean ± standard error. There was a significant decrease in HbA1c in the Placebo (P< 0.048) and combined antioxidant therapy groups (P< 0.05). These improvements could be due to close medical attention or lifestyle changes.

NPDR, non-proliferative diabetic retinopathy; HBA1c, glycated hemoglobin, %, percent, TC, total cholesterol; LDC, low-density cholesterol; HDL, high-density cholesterol; TGC, triglycerides; mg/dl, milligram/deciliter, NS, not significant; WCX, Wilcoxon test, K–W, Kruskal–Wallis test.