Table 2.

Most significantly differentially expressed genes on Day 2

Untreated Vs Hemin			Hemin Vs Hemin + ARID3a shRNA
Gene	Log2 Fold Change	Adj P Value	Gene	Log2 Fold Change	Adj P Value
TXNIP	5.24	6.25E-15	SH3BGR	2.29	4.02E-07
OSGIN1	3.68	3.63E-16	HSPA5	2.05	7.51E-10
HBZ	3.52	6.64E-16	HERPUD1	1.83	4.88E-11
AKR1C1	3.01	1.89E-14	ARG2	1.75	2.36E-09
SQSTM1	2.99	1.22E-24	ALDH1A1	1.61	7.07E-07
MCM5	2.74	1.07E-18	NFE4	1.43	3.92E-12
HBA2	2.54	2.68E-15	SEC24D	1.40	3.58E-07
HBE1	2.47	3.58E-21	BEX2	1.29	4.11E-06
NQO1	2.41	2.22E-32	CREG1	1.28	2.85E-06
HBG2	2.12	2.33E-15	LCP1	1.22	4.33E-07
GCLM	2.08	5.83E-19	SERPINH1	1.20	5.91E-06
PPP1R15A	2.05	2.15E-13	RTN4	1.16	3.14E-08
FTL	2.02	3.63E-16	ACOT13	1.15	6.60E-07
HBA1	1.98	3.73E-13	TDP2	1.11	1.49E-07
HBG1	1.94	1.02E-11	TPM4	1.11	4.53E-08
TXNRD1	1.52	9.58E-12	CTSD	1.11	1.78E-08
FTH1	1.47	4.70E-12	PGD	1.05	3.26E-06
CREM	1.41	1.28E-14	ACTB	1.02	2.38E-06
TXN	1.20	6.53E-14	CTSB	1.02	1.39E-06
PRKCSH	−1.18	3.70E-16	SND1	0.96	8.32E-07
FKBP2	−1.44	1.47E-11	COPA	0.89	2.56E-07
UCA1	−1.52	6.71E-13	GSR	0.88	2.85E-06
SERPINH1	−1.60	1.47E-11	ANXA5	0.88	1.47E-10
PDIA3	−1.63	2.29E-19	SEC61A1	0.80	1.54E-06
DNAJB11	−1.69	4.11E-14	CALU	0.80	1.71E-09
AC068631.2	−1.95	9.98E-12	SSX1	0.77	1.23E-07
HSP90B1	−1.97	3.99E-19	NQO2	0.73	5.36E-06
HERPUD1	−1.99	2.64E-14	PSMC1	0.68	1.35E-06
NMU	−2.01	3.65E-11	SEM1	0.61	4.33E-07
HYOU1	−2.07	7.01E-19	TNNI3	−1.04	8.32E-07
PDIA6	−2.19	2.54E-17	VARS	−1.06	2.82E-07
MANF	−2.24	8.93E-16	LINC01029	−1.10	1.26E-06
PDIA4	−2.35	1.43E-14	MARCKSL1	−1.14	4.84E-07
HSPA5	−2.35	7.91E-14	HEMGN	−1.95	7.51E-10
CALR	−2.57	9.34E-17	TXNIP	−4.15	9.81E-11