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. 2021 Jul 27;2:256–262. doi: 10.1109/OJEMB.2021.3100416

TABLE II. Statistically Significant n-SNP Interactions Per Method and SNP Encoding.

Initial Encoding Binary Encoding Initial Encoding Binary Encoding
2-SNP interactions Logistic Inline graphic
rs17225354 (ITGA4) & rs6721763 (ITGA4) ✓ ✓
rs17225354 (ITGA4) & rs281437 (ICAM1) ✓ ✓ ✓
rs17225354 (ITGA4) & rs1250258 (FN1) ✓ ✓
rs2076074 (SELP) & rs6721763 (ITGA4) ✓ ✓
rs11689738 (ITGA4) & rs281437 (ICAM1) ✓ ✓ ✓ ✓
rs11689738 (ITGA4) & rs6721763 (ITGA4) ✓ ✓
3-SNP interactions Logistic Inline graphic
rs17225354 (ITGA4) & rs281437 (ICAM1) & rs1250258 (FN1) ✓ ✓
rs2076074 (SELP) & rs6721763 (ITGA4) & rs281437 (ICAM1) ✓ ✓