Table 2. Significant variables for the severity of the patients admitted due to COVID-19 in the bivariate analysis.
| Variable | ICU/MV N (%)N = 225 (39.8) | RR (95% CI) | P-value |
|---|---|---|---|
| Age (years) | |||
| < 60 | 100 (33.0) | 1 | |
| 61 to 69 | 65 (48.1) | 1.46 (1.15 to 1.85) | 0.004 |
| > 70 | 60 (47.2) | 1.43 (1.12 to 1.83) | 0.002 |
| Comorbidities | |||
| Hypertension | 122 (46.0) | 1.34 (1.09 to 1.64) | 0.005 |
| Diabetes mellitus | 78 (47.9) | 1.31 (1.07 to 1.61) | 0.010 |
| Obesity | 48 (53.3) | 1.43 (1.14 to 1.79) | 0.002 |
| Neoplasia | 24 (54.5) | 1.41 (1.06 to 1.89) | 0.020 |
| Number of comorbidities | |||
| None | 46 (26.3) | 1 | |
| 1 | 70 (42.7) | 1.62 (1.20 to 2.20) | 0.002 |
| ≥ 2 | 109 (48.2) | 1.84 (1.38 to 2.43) | < 0.001 |
| Clinical alterations upon admission | |||
| Altered level of consciousness | 45 (70.3) | 1.96 (1.61 to 2.38) | < 0.001 |
| Vasoactive amines | 29 (96.7) | 2.64 (2.32 to 3.00) | < 0.001 |
| SpO2 < 93% | 82 (71.3) | 2.21 (1.85 to 2.65) | < 0.001 |
| SpO2/FiO2 Ratio ≤ 315 | 97 (84.3) | 2.93 (2.48 to 3.47) | < 0.001 |
| Supplemental O2 requirement | 130 (63.1) | 2.39 (1.95 to 2.92) | < 0.001 |
| Laboratory and imaging tests upon admission | |||
| C-Reactive Protein > 100 mg/L | 141 (56.6) | 2.13 (1.71 to 2.66) | < 0.001 |
| Lactate (ABG) ≥ 1.6 mmol/L | 74 (54.0) | 1.44 (1.17 to 1,76) | < 0.001 |
| Troponin ≥ 14 ng/L | 92 (53.8) | 1.58 (1.27 to 1.98) | < 0.001 |
| Lymphocytes < 1,000 /Ul | 123 (52.3) | 1.70 (1.38 to 2.08) | < 0.001 |
| Urea ≥ 50 mg/dL | 83 (53.9) | 1.55 (1.27 to 1.90) | < 0.001 |
| Creatinine > 1.2 mg/dL | 76 (52.8) | 1.48 (1.21 to 1.81) | < 0.001 |
| GOT/AST ≥ 37 U/L | 106 (42.7) | 1.32 (1.01 to 1.73) | 0.039 |
| INR ≥ 1.3 | 64 (55.2) | 1.44 (1.17 to 1.78) | 0.001 |
| Altered chest x-ray | 189 (43.5) | 2.00 (1.36 to 2.94) | < 0.001 |
| Need of NIV at some time during hospitalization | 21 (87.5) | 2.32 (1.93 to 2.80) | < 0.001 |
Frequency (percentage); RR = Relative risk; CI = Confidence interval; O2 = oxygen; SpO2 = peripheral oxygen saturation; SpO2/FiO2 Ratio = the ratio between the peripheral oxygen saturation and the fraction of inspired oxygen; ABG = arterial blood gas; NIV = non-invasive ventilation.