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. 2022 Mar 3;14:119–128. doi: 10.2147/CEOR.S340290

Table 3.

Healthcare Costs in the Non-Matched Study Sample

Total Cost, Stratified by Service Setting, Mean (SD) Xtampza ER (N=464) OxyContin (N=1927) P-value*
Prescription cost $7492 (9098) $8754 (13,526) 0.016**
Cost of medicines used in the treatment of OUD $88 (556) $90 (571) 0.951
 Buprenorphine cost $40 (304) $40 (305) 0.993
 Methadone cost $0 (1) $1 (12) 0.367
 Naloxone cost $48 (464) $49 (475) 0.983
 Naltrexone cost $0 (0) $1 (28) 0.624
 IR opioid cost $324 (1015) $356 (1156) 0.581
 ER opioid cost $2645 (1905) $3141 (3171) <0.001**
Outpatient cost $8666 (17,978) $10,226 (21,287) 0.106
OUD-related outpatient cost $177 (1876) $184 (1617) 0.934
Inpatient cost $5037 (26,177) $7748 (32,404) 0.057
OUD-related inpatient cost $91 (908) $388 (3597) 0.001**
ED-related cost $1435 (4283) $1657 (5992) 0.451
OUD-related ED cost $54 (553) $32 (359) 0.418
Total cost $22,630 (37,263) $28,386 (46,188) 0.005**
OUD-related total cost $322 (2151) $604 (4443) 0.048**

Notes: *Independent t-test was performed to assess differences for continuous variables. ** Statistically significant difference (p<0.05). Bold text marks main all-cause cost categories.