Table 1.
Clinical data and Hematological profile of ACHD patients with neutropenia compared with a normal Neutrophil count
| Variables | Patients with ACHD neutropenia (n = 23) | Patients with ACHD Normal Neutrophil count (n = 225) | Total | P value |
|---|---|---|---|---|
| Age (months), Median (IQR) | 7 (11) | 11 (22) | 10 (19) | 0.06 |
| Weight (Kg), Median (IQR) | 6 (5.3) | 7 (6) | 6.8 (6) | 0.66 |
| Sex, n (%) | 0.7 | |||
| Male | 12 (52.2) | 108 (48) | 120 (48.4) | |
| Female | 11 (47.8) | 117 (52) | 128 (51.6) | |
| Type of CHD, n (%) | 0.015* | |||
| VSD | 22 (95.6) | 169 (75.1) | 191 (77) | 0.000* |
| ASD | 0 (0) | 37 (16.4) | 37 (14.9) | 0.000* |
| PDA | 1 (4.4) | 19 (8.4) | 20 (8.1) | 0.49 |
| WBC count (× 109/L), Mean (SD) | 7.6 (2.1) | 10.3 (3.6) | 10.1 (3.6) | 0.000* |
| Hemoglobin (g/dL), Mean (SD) | 11.1 (1.5) | 11.9 (1.5) | 11.8 (1.5) | 0.005* |
| Platelet count (× 109/L), Mean (SD) | 328 (103) | 325 (102) | 325.6 (102) | 0.89 |
| Anemia, n (%) | 12 (52.2) | 36 (16) | 48 (19.3) | 0.000* |
| Leukopenia, n (%) | 2 (8.1) | 1 (0.4) | 3 (1.2) | 0.184 |
| Thrombocytopenia, n (%) | 0 (0) | 3 (1.3) | 3 (1.2) | 0.74 |