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. 2021 Feb 4;43(1):315–324. doi: 10.1080/0886022X.2021.1879856

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Characterizations of glomerular function and damage. (A) Start vs endpoint glomerular filtration rates (GFR). (B) Representative FITC-inulin clearance curves from conscious freely moving rats injected with FITC-inulin. (C) Glomerular injury as determined by scoring individual glomeruli for damage; each point is an average of 100 randomly scored glomeruli per kidney. Images are representatives of glomeruli from Masson trichrome stained tissues, from VEH and SCB animals. Two-way ANOVA with Tukey post-hoc was used for significance comparisons. p values are shown for comparisons where p < .05.