. 2022 Mar 8;42(2):161–191. doi: 10.1016/j.cll.2022.02.005

Table 7.

An overview of high-throughput molecular diagnostic platforms for SARS-CoV-2

Platform	Assay	Target 1	Target 2	Target 3	Internal Control	Analytical Sensitivity SARS-CoV-2 RNA c/ml	Platform Run Time	Throughput 24hr	Loading	References
Abbott m2000	Abbott RealTime SARS-CoV-2	RdRp	N		Manufacturer SPC	53⁹²	4 h	470	Batch	92
Abbott Alinity M	SARS-CoV-2 AMP Kit	RdRp	N		Manufacturer SPC (DNA)	50⁹⁰	2 h 35 min to first results	1080	Random Access	90
Hologic Panther®	Aptima® SARS-CoV-2 Assay	Orf1Ab Region 1	Orf1ab Region 2		Manufacturer SPC	83–194¹³⁷^,¹³⁸	3.5 h to the first result	1150	Batch	137 138
Hologic Panther Fusion®	Panther Fusion® SARS-CoV-2 Assay	Orf1Ab Region 1	Orf1ab Region 2		Manufacturer SPC	74–100⁹²^,¹³⁹^,¹⁴⁰	2.4 h to first results	1440	Random Access	92 139 140
Roche Cobas® 6800	cobas® SARS-CoV-2	Orf1ab	E		Manufacturer SPC	<10–85⁹²^,¹⁴¹	3.4 h to first results	1440	Batch	92 141
Roche Cobas® 8800	cobas® SARS-CoV-2	Orf1ab	E		Manufacturer SPC	<10–85⁹²^,¹⁴¹	3.4 h to first results	4128	Batch	92 141
Cepheid Infinity	Xpert Xpress SARS-CoV-2	N	E		Manufacturer SPC	100	50 min per cartridge	Up to 1920	Random Access	95
Thermofisher Amplitude	TaqPath COVID-19 HT	S gene	N	Orf1ab	MS2	N/A	3 h 30 min to first result	8000	Batch	No literature found