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. 2022 Mar 8;14:100228. doi: 10.1016/j.mtadv.2022.100228

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Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 1 — (A) Structure of (3-trihydroxysilyl)propyldimethyl octadecyl ammonium chloride, the active ingredient in Goldshield GS75, which was coated onto the N95 filters and masks to determine whether it would inactivate Alpha and Beta variants of the SARS-CoV-2. (B) Structure of water-stabilized organosilane compound. (C) Structure of the compound chemically bound to a surface. (D) The Gas Chromatography Mass Spectrometry (GCMS) profile of the GS75 solution confirming the presence of two fragmented peaks. (E) The Fourier Transform Infrared spectroscopy (FTIR) spectrum is consistent with a fatty quaternary ammonium structure, confirming the composition of GS75 [[1], [2], [3], [4], [5]]. The micrographs are SEM images of (F) uncoated and (G) GS-75-coated N95 polypropylene fabrics. See also Figs. S6 and S7. [1] G. Socrates, Infrared and Raman Characteristic Group Frequencies – Tables and Charts, 3rd Edition 2005. [2] Know-It-All Spectral Analysis Software, John C. Wiley and Sons, 2020. [3] Know-It-All Library Search, John C. Wiley and Sons, 2020. [4] C.J. Brinker and G.W Scherer, Sol-Gel Science, Academic Press, 1990 pp582-583. [5] R.K. Iler, The Chemistry of Silica, John C. Wiley and Sons, 1979, p639.