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. 2022 Jan 20;42(1):45–54. [Article in Chinese] doi: 10.12122/j.issn.1673-4254.2022.01.05

1.

肝细胞癌中的促癌miRNA

Onco-miRNAs in HCC

No miRNA Name Upregulated in/Prognosis Expression(Log2 Mean) miRNA Name Upregulated in/Prognosis Expression(Log2 Mean)
Tumor Normal P Tumor Normal P
1 hsa-miR-106b-5p tumor/poor 7.76 7.33 0.0000485 25 hsa-miR-3615 tumor/poor 2.84 2.38 0.00427
2 hsa-miR-10b-5p tumor/poor 13.96 10.54 4.24E-16 26 hsa-miR-361-5p tumor/poor 8.29 8.07 0.0218
3 hsa-miR-1180-3p tumor/poor 4.49 3.17 1.58E-09 27 hsa-miR-3677-3p tumor/poor 2.12 0.56 6.03E-13
4 hsa-miR-1226-3p tumor/poor 0.35 0.02 0.000649 28 hsa-miR-3682-3p tumor/poor 0.91 0.15 0.0000125
5 hsa-miR-1266-5p tumor/poor 2.46 0.83 4.8E-08 29 hsa-miR-3928-3p tumor/poor 0.92 0.34 0.000184
6 hsa-miR-1269a tumor/poor 6.04 2.39 2.03E-08 30 hsa-miR-421 tumor/poor 1.71 0.55 2.91E-08
7 hsa-miR-1270 tumor/poor 0.79 0.05 0.0000335 31 hsa-miR-425-5p tumor/poor 7.15 6.79 0.0103
8 hsa-miR-1301-3p tumor/poor 2.93 1.96 0.00000354 32 hsa-miR-452-3p tumor/poor 2.52 1.15 0.0000146
9 hsa-miR-1307-3p tumor/poor 10.4 9.7 0.0000107 33 hsa-miR-452-5p tumor/poor 7.22 5.51 1.15E-07
10 hsa-miR-132-3p tumor/poor 6.25 5.75 0.0011 34 hsa-miR-500a-3p tumor/poor 8.01 7.24 7.37E-08
11 hsa-miR-151a-3p tumor/poor 11.67 10.9 1.12E-10 35 hsa-miR-500a-5p tumor/poor 1.87 1.52 0.00754
12 hsa-miR-183-5p tumor/poor 10.69 8.05 1.06E-09 36 hsa-miR-500b-5p tumor/poor 1.87 1.52 0.00711
13 hsa-miR-185-3p tumor/poor 2.72 2.42 0.0225 37 hsa-miR-501-3p tumor/poor 5.41 4.78 8.15E-07
14 hsa-miR-188-5p tumor/poor 1.54 0.58 4.71E-08 38 hsa-miR-532-3p tumor/poor 5.6 5.34 0.0423
15 hsa-miR-221-5p tumor/poor 1.35 0.65 0.0000216 39 hsa-miR-550a-5p tumor/poor 2.01 1.51 0.00409
16 hsa-miR-222-3p tumor/poor 4.54 3.59 0.00000275 40 hsa-miR-589-5p tumor/poor 6.31 5.35 8.49E-11
17 hsa-miR-25-3p tumor/poor 13.19 12.58 0.0000018 41 hsa-miR-652-3p tumor/poor 4.28 3.93 0.0352
18 hsa-miR-3127-5p tumor/poor 1.45 0.66 0.0000136 42 hsa-miR-769-5p tumor/poor 3.69 3.37 0.0016
19 hsa-miR-3200-3p tumor/poor 0.91 0.18 0.000023 43 hsa-miR-877-5p tumor/poor 0.53 0.08 0.0000231
20 hsa-miR-32-3p tumor/poor 0.51 0.27 0.0458 44 hsa-miR-937-3p tumor/poor 1.13 0.35 0.000323
21 hsa-miR-324-3p tumor/poor 4.17 3.71 0.000115 45 hsa-miR-9-3p tumor/poor 1.13 0.07 0.000271
22 hsa-miR-330-5p tumor/poor 4.06 3.21 0.00000117 46 hsa-miR-940 tumor/poor 0.94 0.38 0.00221
23 hsa-miR-331-5p tumor/poor 1.49 1.09 0.000981 47 hsa-miR-9-5p tumor/poor 8.43 6.78 0.000118
24 hsa-miR-339-3p tumor/poor 2.78 2.35 0.00186 48 hsa-miR-99b-3p tumor/poor 4.43 3.95 0.00657
22 hsa-miR-330-5p tumor/poor 4.06 3.21 0.00000117 46 hsa-miR-940 tumor/poor 0.94 0.38 0.00221
23 hsa-miR-331-5p tumor/poor 1.49 1.09 0.000981 47 hsa-miR-9-5p tumor/poor 8.43 6.78 0.000118
24 hsa-miR-339-3p tumor/poor 2.78 2.35 0.00186 48 hsa-miR-99b-3p tumor/poor 4.43 3.95 0.00657