Table 2.

Cox Regression Analysis for Recurrence-Free Survival at Postoperative Year 2

	Univariate			Multivariate
Variables	HR	95% CI	P value	HR	95% CI	P value
Type of anaesthesia
GA	Reference			Reference
TG	0.702	0.235–2.096	0.527	0.706	0.126–3.941	0.691
Tumour stage
I	Reference			Reference
II	0.851	0.184–3.940	0.837	0.136	0.015–1.743	0.077
III	1.467	0.397–5.419	0.566	0.022	0.001–0.734	0.033
Treatment regime
Surgery only	Reference			Reference
Surgery & chemotherapy	0.979	0.212–4.532	0.978	5.372	0.438–65.935	0.189
Surgery & radiation	5.394	0.682–42.657	0.110	17.585	0.641–6482.186	0.080
Other treatment	0.960	0.207–4.443	0.958	159.206	1.953–12,377.670	0.024
ASA status
I	Reference			Reference
II	0.856	0.288–2.548	0.780	1.207	0.119–12.236	0.874
III	0.722	0.089–5.866	0.760	1.170	0.119–11.507	0.893
Sex
Male	Reference			Reference
Female	0.576	0.200–1.660	0.307	0.682	0.183–2.545	0.569
Smoking status
Yes	Reference			Reference
No	0.838	0.263–2.670	0.764	0.682	0.183–2.545	0.569
Age, yr
Age <60	Reference			Reference
Age ≥60	1.154	0.400–3.326	0.791	1.243	0.374–4.131	0.722
IPSD	1.016	0.996–1.036	0.122	1.018	0.990–1.047	0.192

Notes: Only the clinically meaningful clinicopathologic and perioperative variables were included in the univariate and multivariate ananlysis, which were analysed by Cox proportional hazards regression. Associations with P < 0.05 were considered statistically significant.

Abbreviations: TG, thoracic paravertebral block combined with general anaesthesia alone; GA, general anaesthesia alone; ASA, American Society of Anesthesiologists; HR, hazard ratio; CI, confidence interval; IPSD, intraoperative and postoperative sufentanil dosage.