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. Author manuscript; available in PMC: 2022 Mar 7.
Published in final edited form as: Am J Crit Care. 2021 Nov 1;30(6):e99–e107. doi: 10.4037/ajcc2021599

Table 2.

Multivariable analysis of factors associated with documented CAM-ICU assessments and inappropriate “unable to assess” responses

Documented CAM-ICU IUTA response
Factor Odds ratioa 95% CI P Odds ratioa 95% CI P
Patient related
Age, y
 <65 Reference Reference
 65–80 0.95 0.88–1.02 .16 1.28 0.99–1.65 .06
 >80 0.96 0.87–1.06 .46 1.72 1.25–2.35 .001
Sex
 Male Reference Reference
 Female 1.06 0.99–1.13 .09 1.19 0.94–1.51 .16
Primary language
 English Reference Reference
 Spanish 1.09 0.95–1.24 .22 0.48 0.27–0.87 .02
 Other 0.94 0.83–1.06 .31 1.49 0.94–2.37 .12
Ethnicity
 Non-Hispanic Reference Reference
 Hispanic 1.00 0.91–1.10 >.99 1.44 0.99–2.11 .06
Race
 White Reference Reference
 Non-White 0.95 0.88–1.01 .11 1.46b 1.13–1.89 .005
Clinical
Admission diagnosis category
 Respiratory Reference Reference
 Sepsis 1.04 0.93–1.16 .53 2.37 1.55–3.64 <.001
 Other 0.90 0.81–1.00 .05 1.32 0.87–2.02 .18
Not intubated Reference Reference
Intubated 1.06 0.97–1.15 .20 2.18 1.74–2.74 <.001
Not requiring physical restraints Reference Reference
Physical restraints 1.20 1.09–1.32 <.001 2.15 1.64–2.82 <.001
No propofol infusion Reference Reference
Propofol infusionb 1.14 0.99–1.30 .06 1.93 1.41–2.64 <.001
No midazolam infusion Reference Reference
Midazolam infusionb 0.90 0.76–1.05 .17 1.82 1.05–3.16 .04
No dexmedetomidine infusion Reference Reference
Dexmedetomidine infusionb 1.38 1.18–1.62 <.001 1.69 1.12–2.56 .01
No fentanyl infusion Reference Reference
Fentanyl infusionb 0.92 0.81–1.04 .18 1.98 1.50–2.62 <.001
Workplace
Day shift Reference Reference
Night shift 0.86 0.81–0.91 <.001 0.99 0.93–1.06 .89
Side A Reference Reference
Side B 1.38 1.30–1.48 <.001 0.78 0.60–1.01 .07
Weekend Reference Reference
Weekday 1.02 0.97–1.08 .44 0.91 0.84–0.99 .04
Not July Reference Reference Reference
July 1.06 0.94–1.19 .32 0.51 0.22–1.18 .11

Abbreviations: CAM-ICU, Confusion Assessment Method for the Intensive Care Unit; IUTA, inappropriate “unable to assess.”

a

Calculated by using multivariable logistic regression, with generalized estimating equations to account for repeated time-varying measures (eg, CAM-ICU). For patients admitted multiple times during the data collection period, we confined our analysis to each patient’s first admission. Variance inflation factors were used to evaluate for multicollinearity; none was detected. Higher documentation and inappropriate “unable to assess” response odds ratios represent factors associated with a greater odds of completion of CAM-ICU documentation or inappropriate “unable to assess” scores, respectively.

b

Administered at any time during a 12-hour CAM-ICU documentation period.