Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 22;58(2):169–178. doi: 10.1007/s11626-022-00656-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Figure 2. — Crosstalk of β1 integrin and growth factor receptor signaling regulates clonogenic radiation survival. (A) Clonogenic survival of irradiated GD25β1A and GD25β1B cells on polystyrene (PS) or fibronectin (FN) with or without fetal calf serum (FCS). (B) Representative western blot of caspase-3, cleaved caspase-3 and β-actin expression in serum starved GD25β1A and GD25β1B cells on PS or FN before and 24 h after 6 Gy X-ray irradiation. (C) Representative western blot of the integrin α4, α5, α8, α9, αV subunits and corresponding β-actin expression in GD25β1A and GD25β1B. (D, E) Cell cycle distribution of (D) unirradiated and (E) irradiated GD25β1A and GD25β1B cells on PS or FN with or without FCS. (A–E) Results show mean ± SD (n = 3); t-test FCS vs. no FCS; *P < 0.05; **P < 0.01, ***P < 0.001; t-test 0 Gy vs. 6 Gy; ^#P < 0.05; ^##P < 0.01, ^###P < 0.001.