Table 1.
Demographic MRI and OCT-A parameters for the overall sample and by CSVD cases and controls.
| All | Controls | Age-matched cases | P value1 | All cases | P value2 | |
|---|---|---|---|---|---|---|
| Sex (f;m) | 18; 12 | 6; 4 | 5; 5 | 12; 8 | ||
| Age | 61 ± 10 | 58 ± 5 | 60 ± 10 | 0.853 | 63 ± 11 | 0.475 |
| Fazekas score | 0; 1; 2; 3 | 0 | 1; 2; 3 | 1; 2; 3 | ||
| MoCA | 25 ± 3 | 25 ± 3 | 26 ± 3 | 0.529 | 25 ± 4 | 0.948 |
| Vessel Density, superficial | 0.278 ± 0.018 | 0.281 ± 0.015 | 0.279 ± 0.019 | 0.579 | 0.276 ± 0.020 | 0.373 |
| Vessel Diameter Index, superficial | 1,956,055 ± 68,017 | 1,979,802 ± 30,639 | 1,949,547 ± 64,953 | 0.075 | 1,944,182 ± 78,558 | 0.100 |
| Vessel Density, deep | 0.242 ± 0.017 | 0.245 ± 0.013 | 0.239 ± 0.021 | 0.529 | 0.240 ± 0.019 | 0.530 |
| Vessel Diameter Index, deep | 1,553,981 ± 64,138 | 1,571,945 ± 59,464 | 1,543,678 ± 76,799 | 0.436 | 1,544,999 ± 65,947 | 0.328 |
| Choriocapillaris reflectivity, mean | 0.905 ± 0.051 | 0.918 ± 0.050 | 0.898 ± 0.043 | 0.631 | 0.899 ± 0.052 | 1.000 |
| Choriocapillaris reflectivity, SD | 0.240 ± 0.01179 | 0.247 ± 0.011 | 0.234 ± 0.012 | *0.029 | 0.237 ± 0.011 | *0.039 |
| NOL | 12 ± 8 | 6 ± 6 | 16 ± 8 | *0.002 | 16 ± 8 | *0.001 |
| WMI | 27.34 × 10–4 ± 44.61 × 10–4 | 2.58 × 10–4 ± 2.57 × 10–4 | 44.08 × 10–4 ± 53.31 × 10–4 | * < 0.0001 | 39.71 × 10–4 ± 50.50 × 10–4 | *0.0001 |
MoCA, Montreal Cognitive Assessment; NOL, number of white matter hyperintensity lesions on magnet resonance imaging; WMI, White Matter Lesion Index; SD, standard deviation; 1Comparison of age matched cases to controls, 2Comparison of all cases to controls.
The numbers are marked with asterisks to highlight statistical significance.