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. 2021 Oct 8;29(3):657–669. doi: 10.1038/s41418-021-00881-1

Fig. 6. Casp1, but not Nlrp1 or Casp6, genetic ablation improves survival in J20 mice.

Fig. 6

Kaplan–Meier survival curves and pairwise comparisons between A WT and J20 mice (p < 0.0001), B J20 and J20/Nlrp1−/− (p = 0.1807), J20/Casp1−/− (p = 0.0030), and J20/Casp6−/− (p = 0.2280) mice, C J20 and J20/Nlrp1+/− (p = 0.3548), J20/Casp1+/− (p < 0.0001), and J20/Casp6+/− (p = 0.6374) mice, D WT and WT/Nlrp1−/−, WT/Casp1−/−, and WT/Casp6−/− mice (no significant differences), and E WT and WT/Nlrp1+/−, WT/Casp1+/−, and WT/Casp6+/− mice (no significant differences).