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. 2022 Mar 7;12:4016. doi: 10.1038/s41598-022-08064-9

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Graft survival and peripheral immune responses. (A) Representative bioluminescent images of the transplanted mGRPs and (B) graft survival over time. The immune modulators didn`t impact the graft survival. (C) Peripheral cytokines measured over time by groups with expected reduction of pro-inflammatory cytokine levels by additional use of immune modulators. mGRPs: glial-restricted precursors; sPIF: synthetic PreImplantation Factor; Tac: Tacrolimus, CB: co-stimulatory blockade. *p < 0.05; **p < 0.01; ***p < 0.001. Data are presented as mean ± SD (one-way analysis of variance (ANOVA) followed by a post–hoc test (Bonferroni test).