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. 2022 Mar 7;12:3682. doi: 10.1038/s41598-022-07540-6

Table 3.

The univariate and multivariate analysis of prognostic factors for 3-year RFS.

Variables Univariate Multivariate
HR 95%CI p-value HR 95%CI p-value
Age (≤ 74, 74 <) 1.23 0.67–1.58 0.721
Gender (male/female) 1.18 0.50–1.42 0.523
BMI (≤ 22/22 <) 1.48 0.89–2.50 0.131
Tumour location (Right side/Left side) 0.91 0.54–1.55 0.749
Histology (Well or Moderate/Others) 1.9 1.26–4.51 0.007 2.43 1.24–4.78 0.010
Depth of tumor invasion (T1·T2/T3·T4) 14.6 3.57–60.0 0.0002 4.98 1.50–16.6 0.009
Lymph node metastasis (− / +) 4.00 2.34–6.82 0.0001 2.78 1.51–5.10 0.001
Lymph invasion (− / +) 3.31 1.90–5.78 0.0001 1.84 0.99–3.42 0.053
Venous invasion (− / +) 2.24 1.16–4.31 0.016 1.28 0.64–2.56 0.490
CEA lebel (normal/high) 2.18 1.300–3.64 0.004 2.13 1.19–3.82 0.011
CA19-9 lebel (normal/high) 3.04 1.74–5.32 0.0003 1.09 0.58–2.04 0.80
GNRI (low/high) 2.87 1.68–4.91 0.0003 2.31 1.28–4.20 0.006