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Efficacy of doses of amoxicillin plus potassium clavulanate resulting in levels in rat plasma simulating those achieved in the plasma of humans against S. pneumoniae N1387 (a), S. pneumoniae 410101 (b), S. pneumoniae 14319 (c), and S. pneumoniae RS1 (d) in an experimental respiratory infection in rats. Data are represented as mean and standard deviation bacterial numbers in the lungs of individual animals.
