Table 2.
Clinical characterization of the sample at baseline and at follow-up.
| Baseline | U | p | r | Follow-up | U | p | r | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HC | DM1 | HC | DM1 | |||||||||||
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | |||||||
| WM lesion load | ||||||||||||||
| GLOBAL | 1.1 | (0.99) | 5.33 | (5.98) | 19.50 | 0.034 | 0.49 | 2.3 | (2.83) | 6.89 | (6.31) | 22.00 | 0.058 | 0.43 |
| Frontal | 0.6 | (0.7) | 1.89 | (2.03) | 27.00 | 0.121 | 0.36 | 1.3 | (1.34) | 2.44 | (2.13) | 31.00 | 0.229 | 0.28 |
| Parieto-occipital | 0.3 | (0.48) | 1.89 | (2.42) | 24.00 | 0.059 | 0.43 | 0.4 | (0.7) | 2.67 | (2.5) | 20.50 | 0.030 | 0.50 |
| Temporal | 0 | (0) | 1.22 | (1.99) | 25.00 | 0.022 | 0.53 | 0 | (0) | 1.56 | (2.19) | 25.00 | 0.022 | 0.53 |
| Basal ganglia | 0.1 | (0.32) | 0.22 | (0.67) | 44.00 | 0.878 | 0.04 | 0.5 | (1.58) | 0.22 | (0.67) | 45.00 | 1.000 | 0.00 |
| Infratentorial | 0.1 | (0.32) | 0.11 | (0.33) | 44.50 | 0.939 | 0.02 | 0.1 | (0.32) | 0 | (0) | 40.50 | 0.343 | 0.22 |
| CTG | 277.25 | (232.23) | 437.43 | (385.21) | ||||||||||
| MIRS | 2.6 | (0.89) | 2.13 | (1.25) | ||||||||||
HC: Healthy Controls; DM1: Myotonic Dystrophy Type 1; SD: Standard Deviation. Descriptive data are shown as mean and SD for WM lesion load, CTG and MIRS.