Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 7;12(3):36. doi: 10.1038/s41408-022-00631-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — A Cell viability assay for DLBCL cell lines treated with tamoxifen (TAM) for 48 h in estrogen-containing culture medium. B Cell viability assay for cell lines treated with tamoxifen for 48 h in estrogen-free culture medium. C IC₅₀ values for DLBCL cell lines treated with tamoxifen for 48 h on normal culture medium and ES-free culture medium. D Western blot of U2932 treated with 10 (T10), 15 (T15), and 20 (T20) µM of tamoxifen in RPMI or ES-free RPMI. The effect of Tamoxifen treatment is shown on apoptosis with PARP and DNA damage with γH2AX. E Cell viability assay for cell lines treated with endoxifen for 48 h. F Cell viability assay for cell lines treated with PHTPP for 48 h. G Cell viability assay for cell lines treated with DPN for 48 h. H Competition assay for U2932 treated with tamoxifen and DPN for 48 h. Data were normalized to the control and plotted as the mean ± standard deviation (SD) of n = 3 in all panels. *P ≤ 0.05.