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. 2022 Mar 7;12:4026. doi: 10.1038/s41598-022-07986-8

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Volcano plot presenting the abundance of alternative splicing events (ASEs) in each experimental comparison: (A) LPS versus controls; (B) PGJ₂ versus LPS, (C) pioglitazone versus LPS; (D) T0070907 versus LPS. The ∆PSI values of each ASE are presented on the X-axis, and the negative logarithmic adjusted p-value is presented on the Y-axis. Horizontal lines are equal to the negative logarithmic value of the adjusted p-value cut-off (0.05). Colored dots represent different types of significant DASEs (adjusted p-value < 0.05), and grey dots represent non-significant ASEs. The most interesting DASEs are labeled with gene symbols. The plots generated in maser bioconductor software.