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. 2022 Mar 7;12:3612. doi: 10.1038/s41598-022-07317-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of endurance exercise on gut microbiota at the genus level in ApoE knockout mice. Heatmap of integrated microbiota abundance among the WT CD, ApoE CD, ApoE WD, and ApoE HD EX groups. Significant differences were assessed using one-way ANOVA followed by a Duncan post hoc test. *Significant difference between ApoE WD and ApoE WD EX; ^#Significant differences among ApoE WD, ApoE CD, and WT CD.