Table 2.

Plasmodium falciparum-K13 mutations in India

States/Districts	Year of study	Mutation observed	Mutation in k13 Propeller region	Assay employed	References
Arunachal Pradesh (Changlang)	2014–2015 2009–2013 2014–2015	F446I R561H A481V A675V D702N	F446I R561H A481V A675V D702N	Molecular marker studies Prospective therapeutics studies Molecular marker studies	Mishra et al. (2016) Mishra et al. (2015) Das et al. (2017)
Mizoram (Lunglei)	2014–2015	A578S, K189T	A578S	Molecular marker studies	Mishra et al. (2016)
Tripura (Gomati)	2014–2015	K189T G533A	G533A	Molecular marker studies	Mishra et al. (2016); Mishra et al. (2015)
West Bengal	2013–2014 2009–2013	G625R N672S R539T	R539T G625R N672S S549Y	Ex vivo Ring-stage survival Assay (RSA 0-3 h) Prospective therapeutics studies	Das et al. (2018) Mishra et al. (2015)
Madhya Pradesh	2012–2014	M579T N657H	M579T N657H	Molecular marker studies	Mishra et al. (2017)