Fig. 1.

Expected diagnostic performance of core needle biopsy (CNB) and fine needle aspiration (FNA). (A) The expected positive predictive value (PPV) and negative predictive value (NPV) for the diagnosis of thyroid malignancy with a variable prevalence of the disease. (B) The diagnosis of thyroid malignancy and noninvasive follicular thyroid neoplasm with papillary-like nuclear feature (NIFTP) with a variable prevalence of the disease. (C) The diagnosis of surgical diseases including malignancy, NIFTP, and benign neoplasm with a variable prevalence of the disease. The thin red and green lines represent the corresponding 95% confidence intervals for PPV and NPV, respectively.