Table 1.
Clinicopathologic Characteristics of Patients
| Characteristic | CNB (n=1,381) | FNA (n=2,223) | P value |
|---|---|---|---|
| Age, yr | 47.1±13.7 | 48.9±16.2 | 0.534 |
|
| |||
| Sex | 0.477 | ||
| Female | 1,045 (75.7) | 1,658 (74.6) | |
| Male | 336 (24.3) | 565 (25.4) | |
|
| |||
| Diagnostic category | |||
| I | 39 (2.8) | 250 (11.2) | <0.001 |
| II | 841 (60.9) | 1,121 (50.4) | <0.001 |
| III | 17 (1.2) | 138 (6.2) | <0.001 |
| IV | 241 (17.5) | 45 (2.0) | <0.001 |
| V | 7 (0.5) | 68 (3.1) | <0.001 |
| VI | 236 (17.1) | 601 (27.0) | <0.001 |
|
| |||
| Histologically confirmed cases | 429 (31.1) | 666 (30.0) | 0.557 |
|
| |||
| Histologic diagnosis | |||
| FA/HA | 70 (16.3) | 27 (4.1) | <0.001 |
| Other benign lesions | 32 (7.5) | 76 (11.4) | 0.042 |
| NIFTP | 15 (3.5) | 7 (1.1) | 0.005 |
| PTC | 244 (56.9) | 539 (80.9) | <0.001 |
| FTC/HCC | 32 (7.5) | 9 (1.4) | <0.001 |
| PDTC/ATC | 9 (2.1) | 2 (0.3) | 0.004 |
| MTC | 3 (0.7) | 3 (0.5) | 0.587 |
| Lymphoma | 18 (4.2) | 0 | <0.001 |
| Other malignancy | 6 (1.4) | 3 (0.5) | 0.091 |
|
| |||
| Nodule size of histologically confirmed cases, cma | |||
| Mean | 2.0±1.5 | 1.1±0.8 | <0.001 |
| ≤1.0 | 111 (25.9) | 428 (64.3) | <0.001 |
| 1.1–2.0 | 143 (33.3) | 177 (26.6) | 0.045 |
| 2.1–3.0 | 101 (23.5) | 38 (5.7) | <0.001 |
| >3.0 | 74 (17.3) | 23 (3.4) | <0.001 |
Values are expressed as mean±standard deviation or number (%).
CNB, core needle biopsy; FNA, fine needle aspiration; FA, follicular adenoma; HA, Hürthle cell adenoma; NIFTP, noninvasive follicular thyroid neoplasm with papillary-like nuclear feature; PTC, papillary thyroid carcinoma; FTC, follicular thyroid carcinoma; HCC, Hürthle cell carcinoma; PDTC, poorly differentiated thyroid carcinoma; ATC, anaplastic thyroid carcinoma; MTC, medullary thyroid carcinoma.
a
The nodule size was determined as the largest diameter measured in the surgical specimen, but if surgery was not performed, it was measured by ultrasound.