TABLE 3.

Incidence and severity of recurrent genital herpes in guinea pigs treated with P-4010 or given placebo during primary HSV-2 infection

Expt no.	No. of animals in recurrent phase	Treatment during primary infection	Total no. of lesions	Mean total lesion score/guinea pig		Mean no. of days on which lesions observed		Lesion score of ≥3			Index of recurrent disease severitya
								% of guinea pigs	Mean no. of days
				No.	% Redb	No.	% Red		No.	% Red
5	18	P-4010	823	48.4	42	27.2	12	94	5.3c	48	1.78
	18	Placebo	1,302	69.3		31.0		100	10.2		2.24
7	26	P-4010	543	17.5c	30	10.9c	20	61	1.6c	64	1.61
	26	Placebo	912	30.4		13.6		77	43		2.24

^aRatio of mean total lesion score per guinea pig to mean number of days on which lesions were observed. 

^b% Red, percent reduction from control (placebo). 

^cSignificantly lower than the control (placebo) value.