Table 3. RILI treatment.

Grade	Treatment
Grade 1: no symptom	No treatment required
	Radiotherapy pauses
	Monitor every 2–3 days
Grade 2: symptom (cough, shortness of breath, chest pain)	Delay oncological treatment
	GCs treatment: prednisone 0.5–1 mg/kg/day orally
	Start antibiotics if infection is suspected
	Alert pneumocystis prophylaxis
≥ Grade 3: hypoxia, respiratory failure, life threatening, ARDS	Stop oncological treatment
	Hospitalization
	Respiratory support
	Imaging, bacterial, hematological examination
	Application of broad-spectrum antibiotics
	GCs treatment: methylprednisolone 2–4 mg/kg/day IV
	Alert pneumocystis prophylaxis and GI prophylaxis

RILI, radiation-induced lung injury; GCs, glucocorticoids; ARDS, acute respiratory distress syndrome; GI, gastrointestinal; IV, intravenous.