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. 2022 Feb;11(2):238–249. doi: 10.21037/tlcr-22-48

Table 2. Correlation between the subtypes of EGFR exon 19 deletion-insertion and IHC.

Exon 19 deletion-insertion subtypes Immunohistochemistry (%)
Napsin A TTF-1 CK7 SPB P value
L747_P753delinsS 85 90 94 100 <0.05
L747_A750delinsP 100 100 100 100
E746_A750delinsQP 100 100 100 50
E746_S752delinsV 100 100 100 100
E746_T751delinsA 100 100 100 100
L747_T751delinsP 100 100 100 0
L747P 66.7 100 100 100
E746_P753delinsVS 100 100 0 0
Others 90 90 90 50

EGFR, epidermal growth factor receptor; IHC, immunohistochemistry; TTF, thyroid transcription factor; CK7, cytokeratin; SPB, surfactant proteins B.