Table 2. Correlation between the subtypes of EGFR exon 19 deletion-insertion and IHC.
Exon 19 deletion-insertion subtypes | Immunohistochemistry (%) | ||||
---|---|---|---|---|---|
Napsin A | TTF-1 | CK7 | SPB | P value | |
L747_P753delinsS | 85 | 90 | 94 | 100 | <0.05 |
L747_A750delinsP | 100 | 100 | 100 | 100 | |
E746_A750delinsQP | 100 | 100 | 100 | 50 | |
E746_S752delinsV | 100 | 100 | 100 | 100 | |
E746_T751delinsA | 100 | 100 | 100 | 100 | |
L747_T751delinsP | 100 | 100 | 100 | 0 | |
L747P | 66.7 | 100 | 100 | 100 | |
E746_P753delinsVS | 100 | 100 | 0 | 0 | |
Others | 90 | 90 | 90 | 50 |
EGFR, epidermal growth factor receptor; IHC, immunohistochemistry; TTF, thyroid transcription factor; CK7, cytokeratin; SPB, surfactant proteins B.