TABLE 2.
Distribution of P. aeruginosa strains by susceptibility to ciprofloxacin and imipenem and number of mutations in topoisomerase genes
MIC of ciprofloxacin (μg/ml) | No. of strains with:
|
|||
---|---|---|---|---|
One mutationa
|
Two mutationsb
|
|||
Imisc | Imird | Imis | Imir | |
2 | 1 | 2 | 0 | 0 |
4 | 3 | 2 | 0 | 0 |
8 | 2 | 0 | 0 | 1 |
16 | 0 | 3 | 0 | 1 |
32 | 0 | 4 | 1 | 2 |
64 | 1 | 2 | 1 | 3 |
128 | 0 | 0 | 1 | 0 |
Strains with a single mutation in gyrA or gyrB.
Strains with one mutation in gyrA and one mutation in parC.
Imis, susceptible to imipenem at MIC range of 0.5 to 4 μg/ml.
Imir, resistant to imipenem at MIC range of 8 to 64 μg/ml.