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. 1999 Jan;43(1):62–66. doi: 10.1128/aac.43.1.62

TABLE 2.

Distribution of P. aeruginosa strains by susceptibility to ciprofloxacin and imipenem and number of mutations in topoisomerase genes

MIC of ciprofloxacin (μg/ml) No. of strains with:
One mutationa
Two mutationsb
Imisc Imird Imis Imir
2 1 2 0 0
4 3 2 0 0
8 2 0 0 1
16 0 3 0 1
32 0 4 1 2
64 1 2 1 3
128 0 0 1 0
a

Strains with a single mutation in gyrA or gyrB

b

Strains with one mutation in gyrA and one mutation in parC

c

Imis, susceptible to imipenem at MIC range of 0.5 to 4 μg/ml. 

d

Imir, resistant to imipenem at MIC range of 8 to 64 μg/ml.