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Molecular docking of RDN components with AhR. (A) AhR forms hydrogen bond bonds with genipin (a), geniposide (b), caffeic acid (c), and chlorogenic acid (d). Effects of RDN on the viability of A549 cells. (B) The cells were cultured with RDN (0.1, 0.2, 0.4, 0.8, or 1.6 mg/mL) in the absence or presence of LPS (20 µg/mL) for 48 h. The data are presented as the means ± SD. *, P<0.05, **, P<0.01 vs. the control. RDN, Reduning; AhR, Aryl hydrocarbon receptor.
