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. 2022 Feb 22;9:790706. doi: 10.3389/fmolb.2022.790706

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Copyright © 2022 Guan, Xu, Sui, Chen, Luan, Jiang, Wei, Long, Zhao, Han, Xu, Lin and Guan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation of the TIC proportion with the expression of D-dimer-related genes. (A–B) Violin plot displaying the ratio differentiation of 22 immune cell types between STAD tumor samples with low or high F3 and F5 expression relative to the median gene expression level. Wilcoxon rank sum for the significance test. (C–D) Scatter plots showing the correlation of the top 3 TIC proportions with F3 and F5 expression (p < 0.05). Pearson’s coefficient for the correlation test. (E) Venn plot displaying the overlapping F3 and F5 cells—namely, CD8 T cells.