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Effect of in vivo treatment with CAM on expression of the TGF-β (A) and IL-6 (B) genes of spleen cells. Tumor cells were administered s.c. on day 0. CAM (2 mg/kg) was administered p.o. on days 8 to 17 and on days 8 to 27. Spleens were removed on day 8 or 28 for the assay. An asterisk indicates statistical significance versus the untreated samples. NS, not significant.
