TABLE 4.

Tumor-neutralizing activity of spleen cells obtained from TB rats treated with CAM

Treatment of spleen cell donora	Tumor wt (g)b
	Day 8	Day 12
TB (day 15)
CAM (days 1–14)	0.85 ± 0.08c	1.97 ± 0.17d
None	1.05 ± 0.17	2.82 ± 0.49
Non-TB
CAM (days 1–14)	1.11 ± 0.16	2.33 ± 0.21
None	1.38 ± 0.16	3.09 ± 0.30
Tumor cell alone	1.31 ± 0.08	2.93 ± 0.33

^a13762NF cells (2 × 10⁶) were administered s.c. on day 0. CAM was administered at 2 mg/kg p.o. on days 1 to 14, with removal of spleens on day 15. 

^bA mixture of tumor cells (1 × 10⁶) and spleen cells (80 × 10⁶) was inoculated s.c. into syngeneic rats, and the tumors were then weighed on days 8 and 12 after the inoculation. Each group contained four to six rats. 

^cP < 0.01 versus the tumor cell-alone group. 

^dP < 0.05 versus the tumor cell-alone group.