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. 2022 Mar 3;11(2):20584601221077074. doi: 10.1177/20584601221077074

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© The Author(s) 2022

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Representative magnetic resonance imaging findings of a 35-year-old woman with hemangioblastoma (Case 1). (a) Axial T1-weighted image (T1WI) showing a cystic mass lesion with a mural nodule in the left cerebellar hemisphere. The cystic lesion is low-intense, while the nodule (arrow) is slightly low-intense compared to the cerebellum. (b) Axial T2WI showing flow voids (arrow) in the mural nodule. (c) Axial contrast-enhanced T1WI showing homogeneous enhancement of the mural nodule (arrow) and no enhancement of the cyst wall. (d) Axial diffusion-weighted image showing that the mural nodule (arrow) is low-intense. (e) A corresponding apparent diffusion coefficient (ADC) map showing increased ADC of the nodule (arrow). The ADC value is 1.6 × 10⁻³ mm²/s. (f) Relative cerebral blood volume (rCBV) map showing increased relative CBV (rCBV) of the nodule. The rCBV ratio, defined as the maximal rCBV (enhanced lesion in yellow circle)/rCBV (contralateral normal white matter in red circle), is 12.42. (g) The intensity–time curve showing only a partial return to the baseline level (yellow line) due to massive leakage of contrast media into the interstitial space.