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. 2022 Feb 22;13:806997. doi: 10.3389/fendo.2022.806997

Table 1.

Baseline demographic and clinical characteristics.

Variables 1st group (n = 401) 2nd group (n = 400) 3rd group (n = 402) p value
Age (years) 61 ± 13 62 ± 12 65 ± 13 <0.001
Male 320 (79.8%) 313 (78.3%) 283 (70.4%) 0.004
Smoking history 266 (66.3%) 247 (61.8%) 223 (55.5%) 0.007
Family history of CAD 113 (28.2%) 118 (29.6%) 82 (20.4%) 0.006
Hypertension 221 (55.1%) 242 (60.5%) 239 (59.6%) 0.253
Diabetes 123 (30.7%) 137 (34.3%) 140 (34.9%) 0.391
Hyperlipidemia 119 (29.9%) 132 (33.1%) 144 (36.1%) 0.178
SBP (mmHg) 132 ± 22 133 ± 22 133 ± 22 0.505
DBP (mmHg) 78 ± 15 79 ± 15 78 ± 15 0.789
Heart rate (/min) 76 ± 16 76 ± 17 77 ± 16 0.491
LVEF (%) 56.76 ± 9.87 57.57 ± 10.62 56.33 ± 10.03 0.236
GRACE score 147 ± 37 151 ± 83 157 ± 62 0.086
 High risk group 197 (54.0%) 197 (52.3%) 232 (64.1%) 0.002
BMI (kg/m2) 26.37 ± 14.25 25.60 ± 3.53 28.05 ± 52.74 0.538
Killip class 0.401
 I 226 (56.4%) 214 (53.5%) 214 (53.2%)
 II 140 (34.9%) 161 (40.3%) 159 (39.6%)
 III 23 (5.7%) 20 (5.0%) 23 (5.7%)
 IV 12 (3.0%) 5 (1.3%) 6 (1.5%)
Degree of pain reliefa (%) 60.14 ± 33.94 63.72 ± 33.03 66.90 ± 33.62 0.026
The time of symptom onset to admission over 12 h (%) 113 (29%) 138 (36.1%) 141 (37.8%) 0.025
Days in hospital 10 (8-13) 10 (8-13) 10 (8-14) 0.898
In-hospital mortality 10 (2.5%) 18 (4.5%) 22 (5.5%) 0.099

aCompared with the highest degree of pain.

Data are shown as mean ± standard deviation or n (%). Data in bold indicate p-values ≤ 0.05.

BMI, body mass index; DBP, diastolic blood pressure; SBP, systolic blood pressure; LVEF, left ventricular eject fraction; CAD, coronary artery disease; GRACE score, global registry of acute coronary events score.