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. 2021 May 5;36(3):309–320. doi: 10.1177/02698811211013583

Table 2.

Epidemiology of mescaline use in the total sample (N = 452).

Characteristic/variable Total sample
N = 452
M (SD) or %
Types of mescaline ever ingested (could select more than one)
 Synthetic 31%
 San Pedro 66%
 Peyote 36%
 Extracted 27%
 Partial extraction 23%
 Other columnar cacti 12%
 Unsure 2%
Types of mescaline you have the most experience with
 Synthetic 17%
 San Pedro 48%
 Peyote 18%
 Extracted 8%
 Partial extraction 7%
 Other columnar cacti 1%
 Unsure 1%
Age first ingested mescaline (n = 451) (years)
 Younger than 18 13%
 18–20 24%
 21–23 17%
 24–26 14%
 27–30 10%
 31–40 11%
 41–50 8%
 Older than 50 4%
Route of administration
 Swallowed 97%
 Snorted 1%
 Smoked/vaporized <1%
 Injected <1%
 Sublingual 2%
 Rectal <1%
Number of lifetime uses of mescaline (n = 448)
 1 22%
 2 10%
 3 14%
 4–10 31%
 11–20 9%
 21 or more 14%
Frequency of use during past 5 years
 More than once a month 3%
 Less than once each month 3%
 Less than once per month but more than once per year 23%
 About once per year 10%
 Less than once per year 60%
Main reason for consuming mescaline
 Explore/connect 74%
 Treatment/healing 8%
 Other (e.g. recreation) 18%
Location
 Indoors 43%
 Outdoors 47%
 Other (e.g. festival) 10%
Who administered the mescaline (could select more than one)
 Self-administration 78%
 Shamanic practitioner 23%
 Other (e.g. peer and friend) 8%
How often do you take more than one dose in a session
 Never 55%
 Sometimes 29%
 Frequently 6%
 Always 10%
Average number of doses consumed in a session (N = 447)
 1 69%
 2 15%
 3 9%
 4 or more 7%
How often consumed mescaline at the same time as other substances
 Never 44%
 Once or twice 32%
 More than a few times 16%
 Always or almost always 8%
Ever experienced craving for mescaline
 Yes 9%
How far in advance do you typically plan before a mescaline session
 No planning 18%
 A few days 26%
 A week 26%
 One month 24%
 More than size months 6%
Source of mescaline
 Purchased 42%
 Gifted 14%
 Grew/found 26%
 Other 18%
Changes in frequency of use in the past year
 Decreased 51%
 Stayed the same 39%
 Increased 10%
How many times tried to reduce consumption (N = 448)
 0 97%
 1 or more 3%
How many times tried to quit consuming (N = 445)
 0 97%
 1 3%
How many times tried to increase consumption (N = 444)
 0 60%
 1 19%
 2 5%
 3 4%
 4 or more 13%
When was the last time consumed
 Within the past month 14%
 Between 1 and 6 months ago 19%
 Between 6 and 12 months ago 12%
 More than 1 year ago 55%
Ever arrested or in trouble with the law because of mescaline
 Yes 1%
Every been in therapy/psychiatric services as a result of mescaline
 Yes <1%
Ever sought medical treatment as a result of mescaline
 Yes 0%
What are the potential psychological or spiritual applications of mescaline (could select more than one)
 Personal growth 90%
 Spiritual growth 87%
 Psychotherapeutic work 81%
 Enhancing cognitive abilities 61%
 Enhancing creative abilities 76%
Number of other people during session (also using mescaline) 4.7 (1.1)
Number of other people during session (not also using mescaline) 1.4 (5.6)

Variables may not be equal to 100% due to the rounding error. N is varied due to participants choosing “prefer not to answer” on specific items.