Table 4.
Disorders previously associated with the miRNAs of the endometriosis—signature.
| miRNAs | Previously described | Endometriosis field | Benign disorder | Malignant disorder |
|---|---|---|---|---|
| hsa-miR-3622a-3p | Yes | No | – | Colorectal cancer |
| hsa-miR-504-3p | Yes | No | Marker of nonalcoholic fatty liver disease | |
| hsa-miR-124-3p | Yes | Yes | Peripheral arterial disease, Hypertension, acute respiratory distress syndrom, Parkinson | Ovarian cancer, HCC, Gastric cancer, Glioma, breast cancer |
| hsa-miR-3923 | Yes | No | Pancreatic cancer, Predict metastasis in breast cancer | |
| hsa-miR-5004-3p | Yes | No | SARS Cov 2 | |
| hsa-miR-520h | Yes | No | Diabetic nephropathy | Breast cancer, Colorectal cancer, Renal cancer |
| hsa-miR-6826-5p | Yes | No | Cervical cancer | |
| hsa-miR-1180-5p | Yes | No | Wilm's tumor, Bladder cancer | |
| hsa-miR-3168 | Yes | No | HCC | |
| hsa-miR-3185 | Yes | No | Associated with death by mechanical asphyxia, CHC | |
| hsa-miR-4674 | Yes | No | Alzheimer disease | Associated with distant metastasis in prostatic cancer |
| hsa-miR-4764-5p | Yes | No | Associated with Rhumatoid arthritis | |
| hsa-miR-516a-3p | Yes | No | Breast cancer, cirrhosis, gastric cancer | |
| hsa-miR-542-5p | Yes | No | Diabetic retinopathy, myocardial injury | Osteosarcoma, breast cancer, gastric cancer, colorectal cancer |
| hsa-miR-1253 | Yes | No | Vascular Smooth muscle, Hypertension complications, | Medulloblastoma, NSCLC, HCC |
| hsa-miR-1292-5p | Yes | No | Gastric cancer | |
| hsa-miR-138-1-3p | Yes | No | Nasopharyneal carcinoma, Lung cancer, thyroid cancer, Renal cancer | |
| hsa-miR-1910-5p | Yes | No | Associated with response to oxydative stress | |
| hsa-miR-216b-3p | Yes | No | Lung cancer, Pancreatic cancer | |
| hsa-miR-29b-1-5p | Yes | No | Helicobacter Pylori, ischemia, cardiomyocytes, endometrium repair | Triple negative breast cancer, colon cancer, oral squamous cell carcinoma, bladder cancer |
| hsa-miR-30e-3p | Yes | No | Nervous system, Cardiomyocytes | Glioma, Hepatocellular carcinoma, ovarian cancer, renal carcinoma |
| hsa-miR-3122 | Yes | No | Functional polymorphisms associated with breast cancer susceptibility in Chinese Han population | |
| hsa-miR-4703-5p | Yes | No | Pancreatic cancer | |
| hsa-miR-4715-5p | Yes | No | Lung cancer | |
| hsa-miR-4749-5p | Yes | No | Glioblastoma | |
| hsa-miR-4999-5p | Yes | No | Colorectal | |
| hsa-miR-6075 | Yes | No | Pancreatic and biliary tract cancers, lung cancers | |
| hsa-miR-6509-5p | Yes | No | Hepatocellular carcinoma | |
| hsa-miR-6875-3p | Yes | No | Hepatocellular carcinoma | |
| hsa-miR-1278 | Yes | No | Papillary cancer, lung cancer, ovarian cancer | |
| hsa-miR-1973 | Yes | No | Spermatogenic impairments, biomarker for detecting T21 | Prostate cancer, Hodgkin lymphoma, early colon carcinoma, renal cancer |
| hsa-miR-203a-5p | Yes | No | Peridontis, foot and mouth virus | Cervical cancer, lung cancer, oropharyngeal cancer |
| hsa-miR-208a-3p | Yes | No | Acute myocardial infarction and cardiac remodeling | Colorectal cancer, osteosarcoma |
| hsa-miR-208a-5p | Yes | No | Bladder cancer | |
| hsa-miR-3691-5p | Yes | No | Hepatocellular cancer, lung cancer | |
| hsa-miR-375-5p | Yes | No | Marker of Diabetes type 1 | Teratoma in testicular cancer |
| hsa-miR-3939 | Yes | No | Diabetic retinopathy and type 2 diabetes metillus | |
| hsa-miR-4260 | Yes | No | Acute myeloid leukemia, colorectal cancer | |
| hsa-miR-4295 | Yes | No | Hemangioma | Osteosarcoma, head and neck carcinoma, bladder cancer, glioma, gastric cancer, ductal pancreatic carcinoma, Non small cells lung cancer |
| hsa-miR-4296 | Yes | No | Osteosarcoma | |
| hsa-miR-4455 | Yes | No | Gastric cancer | |
| hsa-miR-4536-3p | Yes | No | Non-small cell lung cancer | |
| hsa-miR-4750-3p | Yes | No | Pancreatic cancer | |
| hsa-miR-514b-5p | Yes | No | Colorectal cancer | |
| hsa-miR-5572 | Yes | No | Sporadic amyotrophic lateral sclerosis | |
| hsa-miR-5702 | Yes | No | Non-small cell lung cancer, triple negative breast cancer | |
| hsa-miR-573 | Yes | No | Intervertebral disc degeneration, rheumatoid arthritis | Pancreatic cancer, prostate cancer, hepatocellular carcinoma, BRCA1—Mediated breast cancers, Melanoma, gastric cancer, cervical cancer, lung cancer |
| hsa-miR-6813-5p | Yes | No | Breast cancer | |
| hsa-miR-6872-3p | Yes | No | Human cartilage | |
| hsa-miR-7109-5p | Yes | No | Oral squamous cell carcinoma | |
| hsa-miR-7150 | Yes | No | Human cartilage | – |