Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 8;12:4058. doi: 10.1038/s41598-022-07918-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

The landscape of CD163 and CD61. Representative images of (A) control and (B) COVID-19 infected lung sections showing increased CD163 staining in COVID-19 cases, with (C) mean Intensities of CD163 in control and COVID-19 samples. The difference in the mean intensities was calculated using Wilcox test Significance denoted by exact P values (n = 21 images from 6 control lung tissue sections and n = 157 images from 36 COVID-19 lung tissue sections). Detection of CD61 protein in representative sections of (D) control and (E) COVID-19 lung. (F) Mean intensity levels of CD61 staining in control and COVID-19 lungs. (n = 20 images from 6 control lung tissue section and n = 94 images from 26 COVID-19 lung tissue section). (G, H) Intensities of CD163 (n = 21 images/group) and CD61 (n = 20 images/group) protein in control and COVID-19 lung section after random sampling analysis. The difference in the mean intensities was calculated using the Wilcox test. Significance denoted by exact P values. (I, J) Correlation between ACE2-CD163 and ACE2-CD61 has been shown. A regression line was calculated using by fitting a linear model to the data. Label at the top shows correlation value (R) and P value for the linear fit.