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. 2022 Jan 4;114(3):372–380. doi: 10.1093/jnci/djab210

Table 2.

Association of baseline factors and cumulative incidence of major financial hardshipa

Factor Cumulative incidence in % of patients (95% CI), %
Follow-up assessment time
3 months 6 months 9 months 12 months
Age, y
 <65 44.7 (38.1 to 51.0) 62.3 (55.6 to 68.2) 69.9 (63.4 to 75.5) 73.7 (66.4 to 79.6)
 ≥65 38.2 (30.0 to 46.3) 52.2 (43.5 to 60.3) 59.1 (50.3 to 66.9) 68.1 (58.6 to 76.0)
Sex
 Female 41.7 (33.4 to 49.8) 57.6 (48.9 to 65.4) 66.6 (58.0 to 73.9) 69.6 (60.8 to 76.7)
 Male 42.6 (36.0 to 48.9) 59.1 (52.3 to 65.2) 65.4 (58.8 to 71.3) 72.4 (64.9 to 78.5)
Race
 Non-White 43.6 (33.5 to 53.2) 60.4 (49.8 to 69.5) 68.0 (57.4 to 76.5) 73.9 (59.4 to 83.9)
 White 41.8 (35.8 to 47.6) 57.9 (51.7 to 63.5) 65.2 (59.1 to 70.6) 70.3 (64.1 to 75.6)
Marital status
 Not married or partnered 42.3 (34.2 to 50.2) 59.7 (51.2 to 67.2) 66.2 (57.7 to 73.3) 69.0 (60.5 to 76.1)
 Married or partnered 40.3 (33.6 to 46.8) 56.4 (49.4 to 62.8) 64.6 (57.7 to 70.7) 72.2 (64.0 to 78.8)
Income
 <$50 000/year 43.8 (36.9 to 50.5) 59.5 (52.4 to 65.9) 67.1 (60.1 to 73.1) 72.7 (65.6 to 78.6)
 ≥$50 000/year 38.0 (30.2 to 45.7) 56.0 (47.6 to 63.5) 63.5 (55.2 to 70.7) 69.1 (59.3 to 77.1)
 <$100 000/year 44.4 (38.6 to 50.0) 60.3 (54.4 to 65.7) 67.9 (62.1 to 73.0) 72.9 (67.0 to 77.9)
 ≥$100 000/year 27.7 (17.4 to 38.9) 47.7 (35.0 to 59.3) 55.5 (42.4 to 66.7) 64.9 (45.6 to 78.8)
Education
 ≤High school/GED 43.1 (34.8 to 51.1) 55.9 (47.3 to 63.7) 63.1 (54.5 to 70.5) 72.1 (62.3 to 79.7)
 >High school 41.7 (35.2 to 48.1) 60.2 (53.4 to 66.3) 67.7 (61.0 to 73.4) 70.4 (63.6 to 76.2)
Insurance status
 Suboptimal insuranceb 39.4 (28.0 to 50.6) 54.9 (42.5 to 65.7) 67.8 (55.3 to 77.5) 72.4 (59.2 to 82.0)
 Private/Medicare/military 42.9 (37.2 to 48.5) 59.4 (53.5 to 64.8) 65.4 (59.6 to 70.6) 70.8 (64.6 to 76.2)
 Medicare 37.4 (29.5 to 45.4) 52.5 (43.8 to 60.4) 58.5 (49.8 to 66.2) 64.7 (55.6 to 72.5)
 Non-Medicare 45.3 (38.6 to 51.7) 62.3 (55.6 to 68.3) 70.5 (64.0 to 76.0) 75.8 (68.1 to 81.9)
 Medicaid 50.0 (34.3 to 63.8) 65.9 (49.5 to 78.1) 77.6 (61.3 to 87.7) 85.4 (66.9 to 94.0)
 Non-Medicaid 41.2 (35.8 to 46.5) 57.5 (51.9 to 62.7) 64.3 (58.7 to 69.3) 69.3 (63.3 to 74.5)
 Uninsured 55.6 (17.5 to 82.0) 55.6 (17.5 to 82.0) 77.8 (28.1 to 95.1) 77.8 (28.1 to 95.1)
 Insured 41.9 (36.7 to 47.0) 58.6 (53.3 to 63.5) 65.6 (60.3 to 70.3) 71.1 (65.4 to 76.0)
Total assets
 <$25 000 47.1 (40.0 to 53.9) 63.5 (56.3 to 69.8) 69.3 (62.2 to 75.3) 75.0 (66.8 to 81.5)
 ≥$25 000 33.7 (26.5 to 41.1) 50.6 (42.6 to 58.1) 60.3 (52.2 to 67.5) 65.7 (57.2 to 72.9)
 <$50 000 47.3 (40.6 to 53.6) 62.4 (55.7 to 68.4) 68.3 (61.8 to 74.0) 74.8 (67.2 to 80.9)
 ≥$50 000 30.5 (22.8 to 38.5) 49.6 (40.7 to 57.9) 59.9 (50.9 to 67.8) 64.0 (54.7 to 71.9)
 <$100 000 46.7 (40.5 to 52.6) 62.8 (56.6 to 68.3) 68.6 (62.6 to 73.9) 74.9 (68.4 to 80.4)
 ≥$100 000 25.5 (17.2 to 34.7) 43.6 (33.4 to 53.4) 55.7 (44.9 to 65.2) 58.9 (47.6 to 68.5)
Employment
 Unemployed 36.0 (28.1 to 43.9) 51.0 (42.4 to 58.9) 57.7 (49.0 to 65.4) 62.9 (53.8 to 70.7)
 Any employmentc 46.2 (39.5 to 52.6) 63.3 (56.5 to 69.2) 71.1 (64.6 to 76.6) 76.2 (69.2 to 81.9)
Employment (<65 years)
 Unemployed 38.2 (24.0 to 52.3) 58.8 (42.6 to 71.9) 65.7 (49.3 to 78.0) 65.7 (49.3 to 78.0)
 Any employmentc 46.2 (38.8 to 53.2) 63.1 (55.6 to 69.6) 70.9 (63.7 to 77.0) 75.5 (67.2 to 82.0)
Homeowner
 No 42.3 (33.4 to 50.8) 60.2 (50.9 to 68.3) 66.1 (56.9 to 73.8) 71.8 (62.3 to 79.2)
 Yes 40.5 (34.2 to 46.7) 56.4 (49.8 to 62.5) 64.7 (58.2 to 70.5) 69.9 (62.8 to 76.0)
a

Financial hardship that includes all protocol-specified components including new debt accumulation. CI = confidence interval; GED = general education development.

b

Defined as including Medicaid (including “dual eligible” patients with Medicare + Medicaid) or no insurance.

c

Includes full-time employment, part-time employment, self-employed, and on leave from full-time employment.