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. 2022 Jan 28;63(2):192–200. doi: 10.4111/icu.20210382

Table 4. Comparison of the patients diagnosed with prostate cancer according to birth season (summer vs. winter).

Variable Birth season p-value
Summer Winter
Number of patients 10 23
Age (y) 67.5±7.5 71.7±8.2 0.181
Digit ratio 0.934±0.023 0.935±0.037 0.988
PV (mL) 40.6±17.1 50.2±21.4 0.218
PSA (ng/mL) 50.59±48.61 19.22±22.49 0.078
PSAD (ng/mL/mL) 1.442±1.594 0.438±0.585 0.081
Number of positive cores 8.70±3.34 6.35±3.95 0.111
Max core cancer volume (%) 53.69±24.47 39.27±28.42 0.174
Max sum of GS 7.30±1.06 6.83±0.98 0.223
5 0 1 0.362
6 2 9
7 5 7
8 1 5
9 2 1
Max primary GS 3.70±0.67 3.48±0.51 0.307
3 4 12 0.284
4 5 11
5 1 0
Max secondary GS 3.60±0.70 3.35±0.65 0.323
2 0 1 0.768
3 5 14
4 4 7
5 1 1

Values are presented as number only or mean±standard deviation.

PV, prostate volume; PSA, prostate-specific antigen; PSAD, PSA density; GS, Gleason score.

According to the definition of the solar season, the birth seasons were set as follows. Summer: May, June, and July and winter: November, December, and January.

Student’s t-test and chi-squared test were used.