Table 1.
Association of CelTIL score with event-free survival and overall survival in NeoALTTO
| Variable and type of analysis | Event-free survival |
Overall survival |
||
|---|---|---|---|---|
| HR (95% CI) | P a | HR (95% CI) | P a | |
| CelTIL high vs low | ||||
| Univariate | 0.51 (0.30 to 0.85) | .01 | 0.43 (0.22 to 0.84) | .01 |
| Multivariable | 0.40 (0.17 to 0.94) | .04 | 0.43 (0.20 to 0.92) | .03 |
| CelTIL as a continuous variable | ||||
| Univariate | 0.83 (0.73 to 0.95) | .006 | 0.85 (0.72 to 1.01) | .06 |
| Multivariable | 0.78 (0.62 to 1.00) | .05 | 0.85 (0.71 to 1.03) | .09 |
a
All statistical tests were 2-sided. CelTIL = score based on tumor cellularity and tumor infiltrating lymphocytes at day 14; CI = confidence interval; HR = hazard ratio.