Figure 1.

GPR15L expression in the skin with several types of inflammation in mice and humans. (A) Quantitative RT-PCR analysis of GPR15L mRNA levels in the lesional skin of mice with helper T lymphocyte-independent irritant dermatitis and with three immune types of skin inflammation. Results were normalized to glyceraldehyde-3-phosphate dehydrogenase (Gapdh) expression (error bars, SD; n ≥ 5 per group). (B) GPR15L protein expression in healthy human skin and lesional skin from patients with atopic dermatitis or psoriasis. Representative results from the three or more cases are shown. Upper panels, low power (a scale bar, 200 µm); Lower panels, high power (a scale bar, 20 µm).