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. Author manuscript; available in PMC: 2022 Mar 8.
Published in final edited form as: Clin Transplant. 2019 Oct 6;33(11):e13721. doi: 10.1111/ctr.13721

TABLE 4.

Reports of domino liver transplantation from patients with metabolic disorders

Authors Reference Domino donor diagnosis Domino recipient diagnosis Number of domino liver recipients Domino recipient developed donor disease
Celik, et al JIMD Rep. 2019 Jun 19;48(1):83–89 MSUD Propionic Acidemia, Crigler-Najjar Syndrome, Carbamoyl phosphate synthetase deficiency 4 No
Qu, et al Clin Res Hepatol Gastroenterol. 2019 Mar 7. pii: S2210–7401(19)30039–7 Hyperhomocysteinemia Cholangiocarcinoma 1 Yes
Herden U, et al Liver Transpl. 2019 Jun;25(6):889–900 MSUD Various diagnoses 15 No
Vollmar, et al Transpl Int. 2018 Nov;31(11):1207–1215 Amyloidosis Various diagnoses 23 Yes
Karina, et al Transplantation. 2019 Mar;103(3):536–543 MSUD Various diagnoses 11 No
Golbus JR, et al J Clin Lipidol. 2017 Sep - Oct;11(5):1284–1288 Familial hypercholesterolemia Primary Sclerosing Cholangitis 1 Yes
Matsunami M, et al Pediatr Transplant. 2015 May;19(3):E70–4 MSUD Protein C deficiency 1 No
Khanna, et al JIMD Rep. 2016;25:87–94. Epub 2015 Jul 29 Methyl malonic acidemia Primary Sclerosing Cholangitis 1 No

Note: Literature review of domino liver transplantation (DLT) from donors with metabolic diseases. Note that only recipients of domino livers from patients with maple syrup urine disease (MSUD) and methylmalonic acidemia did not develop the disease.