Table 2.
Number of affected fetuses with Hb E-β0-thalassemia according to β-thalassemia mutations in trans of Hb E mutation and number of fetuses with co-inheritance of α0-thalassemia
| β-thalassemia mutations | No | (%) | Number of fetuses with α0-thalassemia (SEA) (%) |
|---|---|---|---|
| CD 41/42 (-TTCT) | 199 | (48.0) | 11 (2.7) |
| CD 17 (A-T) | 115 | (27.7) | 7 (1.7) |
| IVSI-1 (G-T) | 26 | (6.3) | 2 (0.5) |
| IVSI-5 (G-C) | 19 | (4.6) | |
| CD 71/72 (+A) | 18 | (4.3) | |
| 3.4-kb deletion | 10 | (2.4) | |
| IVSII-654 (C-T) | 8 | (1.9) | |
| CD 35 (C-A) | 5 | (1.2) | |
| CD 41 (-C) | 3 | (0.7) | |
| CD 26 (C-T) | 2 | (0.5) | |
| CD 27 (+C) | 2 | (0.5) | 1 (0.2) |
| 105 bp del | 2 | (0.5) | |
| FIL del | 1 | (0.2) | |
| CD 43 (G-T) | 1 | (0.2) | |
| CD 30 (G-C) | 1 | (0.2) | |
| CD 15 (-T) | 1 | (0.2) | |
| CD 33/34 (+C) | 1 | (0.2) | |
| CD 95 (+A) | 1 | (0.2) | |
| Total | 415 | (100) | 21 (5.1) |