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Let-7c targeted BACE2 promoter. A. HEK293 cells transfected with pmiR-let-7c or not, and BACE2 expression detected by RT-qPCR. *P<0.05, compared to the control group; B-F. pB2Luc-A, pBACE2-3UTRluc, pB1P-A, pBACE1-3UTRluc and prhβAPPluc transfected into HEK293 cells with pmiR-let-7c or not, respectively, and dual luciferase assay performed 48 hours after transfection. *P<0.05, compared to the control group. Values represent means ± SD, n=3.
