Table 1.
Summary of different metabolic surgical working mechanism, advantages and disadvantages
| Sleeve Gastrectomy | Roux-en-Y Gastric Bypass | Adjustable Gastric Band | Biliopancreatic Diversion | |
|---|---|---|---|---|
| How it works? | ↑Glucose homeostasis | Smaller stomach pouch holds the lesser food | ↑Fullness | Significant ↓absorption of calories |
| ↑Weight loss | ↓Hunger | Slowing down emptiness | ↑Glucose homeostasis | |
| ↓Hunger and ↑Stomach fullness | ↑Fullness | ↑Weight loss | ||
| ↓Absorption of calories | ↓Hunger and ↑Stomach fullness | |||
| Advantages | Simpler procedure than other bariatric surgery | Sustainable weight loss | Least occurrence of complication | Most effective method for the remission of T2DM |
| Can be done with the T2DM patients with other high risk medical conditions | Obesity associated complications remissions are high | AGB can be removed, if needed | Best in weight loss and improvement of obesity | |
| It can be a bridge surgery to other bypass surgeries like SADI-S | Low risk of nutritional deficiencies than other procedures | Lower rate of relapse | ||
| Disadvantages | Irreversible | Complex procedure than sleeve gastrectomy | Several re-arrangements of band to be done during the first years | Complications and mortality are higher than other procedure |
| Worsening of existing reflux disease and/or onset of new | ↑Incidence of micronutrients deficiencies | Weight loss is lower and slower than other procedures | Higher rate of nutritional deficiencies | |
| ↓Effectiveness on metabolism | Possibility of developing ulcer while using non-steroidal anti-inflammatory drugs (NSAID) | Slippage of band movement | ||
| Dumping syndrome |