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. 2022 Feb 15;14(2):1188–1203.

Figure 2.

Figure 2

Cannabidiol induces osteosarcoma cell apoptosis. A, B. Apoptosis of MG63 and HOS cells in response to cannabidiol treatment, as measured by flow cytometry. After cannabidiol treatment (10 µM) for 24 h, representative images (left) and the ratio (right) of apoptotic cells are shown. These histograms show the mean ± SD of three independent experiments. n=3 for each group. **P<0.01 vs. osteosarcoma. C, D. The protein levels of BCL-2, BAX, and cleaved caspase-3 in MG63 and HOS cells of the osteosarcoma and osteosarcoma + cannabidiol groups. n=3 for each group. **P<0.01 vs. osteosarcoma.